Inhibition of Key Digestive Enzymes by Cocoa Extracts and Procyanidins
نویسندگان
چکیده
منابع مشابه
Inhibition of key digestive enzymes by cocoa extracts and procyanidins.
This study determined the in vitro inhibitory effects of cocoa extracts and procyanidins against pancreatic α-amylase (PA), pancreatic lipase (PL), and secreted phospholipase A(2) (PLA(2)) and characterized the kinetics of such inhibition. Lavado, regular, and Dutch-processed cocoa extracts as well as cocoa procyanidins (degree of polymerization (DP) = 2-10) were examined. Cocoa extracts and pr...
متن کاملInhibition of Key Digestive Enzymes by Cocoa Extracts 1 and Procyanidins
We determined the in vitro inhibitory effects of cocoa extracts and procyanidins against pancreatic α-amylase (PA), pancreatic lipase (PL) and secreted phospholipase A2 (PLA2), and characterized the kinetics of such inhibition. Lavado, regular and Dutch-processed cocoa extracts as well as cocoa procyanidins (degree of polymerization (DP) = 2 to 10) were examined. Cocoa extracts and procyanidins...
متن کاملInhibition by cocoa extracts of biosynthesis of extracellular polysaccharide by human oral bacteria.
Extracts of defatted cocoa inhibited the biosynthesis of extracellular polysaccharide by both cell-free and cell-associated streptococcal glucosyltransferases, but did not affect growth or acid production. Both water-insoluble and water-soluble polysaccharide syntheses were inhibited, and the net result was a shift away from adherence-supportive polysaccharide. Inhibition was non-competitive wi...
متن کاملCocoa procyanidins are stable during gastric transit in humans.
BACKGROUND Polyphenolic procyanidins are abundant flavonoid polymers in Western diets. In vitro biological activity has been reported for these compounds, but activity in vivo depends on the amount and chemical nature of the flavonoids reaching the gastrointestinal tract. Degradation of procyanidins under simulated gastric conditions at pH 2.0 has been reported in vitro. OBJECTIVE The objecti...
متن کاملModulation of TNF-α Secretion in Peripheral Blood Mononuclear Cells by Cocoa Flavanols and Procyanidins
Epidemiological reports have suggested that the consumption of foods rich in flavonoids is associated with a lower incidence of certain degenerative diseases, including cardiovascular disease. Flavanols and their related oligomers, the procyanidins CFP, isolated from cocoa can modulate the production and level of several signaling molecules associated with immune function and inflammation in vi...
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ژورنال
عنوان ژورنال: Journal of Agricultural and Food Chemistry
سال: 2011
ISSN: 0021-8561,1520-5118
DOI: 10.1021/jf200180n